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Search ...
Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
p-6Y-ERBB2 I767M [plasma membrane]
Show undefined attributes
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compartment
[Compartment:876] plasma membrane
created
[InstanceEdit:9647197] Orlic-Milacic, Marija, 2019年05月30日
crossReference
[DatabaseIdentifier:11945452] Mondo:0004669
[DatabaseIdentifier:11944899] Mondo:0005575
[DatabaseIdentifier:11945438] Mondo:0015459
[DatabaseIdentifier:11945437] Mondo:0005580
[DatabaseIdentifier:11945225] Mondo:0005012
[DatabaseIdentifier:11944896] Mondo:0008170
[DatabaseIdentifier:11945164] Mondo:0004986
[DatabaseIdentifier:11944895] Mondo:0007254
[DatabaseIdentifier:11944892] Mondo:0004992
[DatabaseIdentifier:9646736] COSMIC:COSV54064925
[DatabaseIdentifier:9646738] COSMIC:COSM4422821
dbId
9647211
disease
[Disease:1500689] cancer
[Disease:1500576] breast cancer
[Disease:1248674] large intestine cancer
[Disease:9630862] esophagus squamous cell carcinoma
[Disease:1500575] ovarian cancer
[Disease:6802273] skin melanoma
[Disease:1493885] bladder carcinoma
[Disease:9632618] nasopharynx carcinoma
[Disease:1655480] salivary gland cancer
displayName
p-6Y-ERBB2 I767M [plasma membrane]
endCoordinate
1255
hasModifiedResidue
[ReplacedResidue:9646735] L-isoleucine 767 replaced with L-methionine
[ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023
[ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139
[ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196
[ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221
[ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222
[ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
inDisease
true
literatureReference
[LiteratureReference:9646435] Activating HER2 mutations in HER2 gene amplification negative breast cancer
[LiteratureReference:9646758] Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification
maxDepth
1
memberOf
[CandidateSet:R-HSA-9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane] - Homo sapiens
[CandidateSet:R-HSA-9664920] p-6Y-ERBB2 KD mutants (EGFR,PI3K) [plasma membrane] - Homo sapiens
[CandidateSet:R-HSA-9664610] p-6Y-ERBB2 KD mutants (EGFR,ERBB3) [plasma membrane] - Homo sapiens
name
p-6Y-ERBB2 I767M
p-6Y-HER2 I767M
p-6Y-ERBB2 Ile767Met
p-6Y-HER2 Ile767Met
referenceEntity
[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType
ReferenceGeneProduct
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-9647211
startCoordinate
23
Referrals
(hasMember)
[CandidateSet:R-HSA-9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane]
[CandidateSet:R-HSA-9664920] p-6Y-ERBB2 KD mutants (EGFR,PI3K) [plasma membrane]
[CandidateSet:R-HSA-9664610] p-6Y-ERBB2 KD mutants (EGFR,ERBB3) [plasma membrane]
[CandidateSet:R-HSA-9664999] p-6Y-ERBB2 KD mutants (EGFR,RAS) [plasma membrane]
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