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Activated TRAF6:p-IRAK2 interacts with TAK1 complex Show undefined attributes

authored

[InstanceEdit:847735] Shamovsky, V, 2010年06月01日

category binding

compartment

created [InstanceEdit:936971] Shamovsky, V, 2010年08月25日

dbId 936960

displayName Activated TRAF6:p-IRAK2 interacts with TAK1 complex

edited

[InstanceEdit:2562589] Shamovsky, V, 2012年11月06日

eventOf

[Pathway:R-HSA-937042] IRAK2 mediated activation of TAK1 complex - Homo sapiens

followingEvent

[Reaction:R-HSA-936991] Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Activated TRAF6:p-IRAK2 interacts with TAK1 complex

orthologousEvent

output

[Complex:R-HSA-936953] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane]

precedingEvent

releaseDate 2010年12月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-936960

summation

[Summation:447018] TAK1-binding protein 2 (TAB2) and/or TAB3, as part of a comp...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-937042] IRAK2 mediated activation of TAK1 complex

(precedingEvent)

[Reaction:R-HSA-936991] Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3

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