Reactome Pathway Database

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Phosphorylation of Cdc25C at Ser 216 by Chk1 Show undefined attributes

authored

[InstanceEdit:75002] Matthews, L, 2003年08月05日 01:10:00

catalystActivity

[CatalystActivity:182636] protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:75002] Matthews, L, 2003年08月05日 01:10:00

dbId 75010

displayName Phosphorylation of Cdc25C at Ser 216 by Chk1

edited

[InstanceEdit:182637] Matthews, L, 2006年07月10日 19:19:59

eventOf

[Pathway:R-HSA-176187] Activation of ATR in response to replication stress - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-9029987] p-S216-CDC25C translocates to the cytosol - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

name

Phosphorylation of Cdc25C at Ser 216 by Chk1

orthologousEvent

output

precedingEvent

releaseDate 2004年07月06日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-75010

summation

[Summation:75013] A recombinant human CHEK1 forms a complex with and phosphory...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-176187] Activation of ATR in response to replication stress

(precedingEvent)

[BlackBoxEvent:R-HSA-9029987] p-S216-CDC25C translocates to the cytosol

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