Reactome Pathway Database

Schema > Reaction > Entries

oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] Show undefined attributes

catalystActivity

[CatalystActivity:70580] L-aspartate:2-oxoglutarate aminotransferase activity of PXLP-K259-GOT1 dimer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

crossReference

dbId 70581

displayName oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]

eventOf

[Pathway:R-HSA-8963693] Aspartate and asparagine metabolism - Homo sapiens

followingEvent

input

isInDisease false

isInferred false

literatureReference

[LiteratureReference:199740] The amino acid sequence of cytosolic aspartate aminotransferase from human liver

maxDepth 1

modified [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日

name

oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]
L-glutamate + oxaloacetate => 2-oxoglutarate + L-aspartate

negativePrecedingEvent

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-5693783] NAALADases hydrolyse NAAG - Homo sapiens

releaseDate 2004年07月06日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-70581

summation

[Summation:179018] Cytosolic aspartate aminotransferase (glutamate oxaloacetate...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-8963693] Aspartate and asparagine metabolism

(precedingEvent)

(reverseReaction)

[Reaction:R-HSA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp

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