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p53-Dependent G1 DNA Damage Response Show undefined attributes

created [InstanceEdit:69508] Khanna, K, 2003年06月05日 08:03:38

crossReference

dbId 69563

displayName p53-Dependent G1 DNA Damage Response

eventOf

[Pathway:R-HSA-69580] p53-Dependent G1/S DNA damage checkpoint - Homo sapiens

goBiologicalProcess [GO_BiologicalProcess:22659] DNA damage response, signal transduction by p53 class mediator

hasDiagram false

hasEHLD false

hasEvent

[Pathway:R-HSA-69541] Stabilization of p53 - Homo sapiens
[Pathway:R-HSA-69560] Transcriptional activation of p53 responsive genes - Homo sapiens
[Reaction:R-HSA-69562] Inactivation of Cyclin E:Cdk2 complexes by p27/p21 - Homo sapiens
[Reaction:R-HSA-187934] Inactivation of Cyclin A:Cdk2 complexes by p27/p21 - Homo sapiens

isInDisease false

isInferred false

lastUpdatedDate 2019年06月12日

literatureReference

maxDepth 4

modified [InstanceEdit:12757879] Weiser, Joel, 2025年08月05日

name

p53-Dependent G1 DNA Damage Response

orthologousEvent

releaseDate 2004年07月06日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:165074] Manfredi, James J

schemaClass Pathway

species

[Species:48887] Homo sapiens

stId R-HSA-69563

summation

[Summation:69579] Most of the damage-induced modifications of p53 are dependen...

updateTrackers

Referrals

(hasEvent)

[Pathway:R-HSA-69580] p53-Dependent G1/S DNA damage checkpoint

(updatedInstance)

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