Reactome Pathway Database

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p53-Dependent G1 DNA Damage Response Show undefined attributes

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10676414

displayName p53-Dependent G1 DNA Damage Response

eventOf

[Pathway:R-XTR-69580] p53-Dependent G1/S DNA damage checkpoint - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:22659] DNA damage response, signal transduction by p53 class mediator

hasDiagram false

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-69563] p53-Dependent G1 DNA Damage Response - Homo sapiens

isInDisease false

isInferred true

maxDepth 4

name

p53-Dependent G1 DNA Damage Response

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:205621] Xenopus tropicalis

stId R-XTR-69563

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-69580] p53-Dependent G1/S DNA damage checkpoint

(inferredTo)

[Pathway:R-HSA-69563] p53-Dependent G1 DNA Damage Response

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