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Activated FGFR4 phosphorylates FRS2 Show undefined attributes

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authored

[InstanceEdit:190908] de Bono, B, 2007年01月10日 10:27:18

catalystActivity

[CatalystActivity:5654419] protein tyrosine kinase activity of Activated FGFR4:FRS2 [plasma membrane]

category transition

compartment

created [InstanceEdit:5654421] Rothfels, Karen, 2014年12月03日

dbId 5654418

deleted

[Deleted:5655568] Deletion of instance: 190353

displayName Activated FGFR4 phosphorylates FRS2

edited

[InstanceEdit:500337] Jupe, S, 2010年02月03日

eventOf

[Pathway:R-HSA-5654712] FRS-mediated FGFR4 signaling - Homo sapiens

followingEvent

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Activated FGFR4 phosphorylates FRS2

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-5654422] Activated FGFR4 binds FRS2 - Homo sapiens

regulatedBy

[NegativeRegulation:R-HSA-5654420] Negative regulation by 'Activated FGFR4:p-8T-FRS2 [plasma membrane]'

releaseDate 2010年03月16日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

revised

[InstanceEdit:1493881] Rothfels, K, 2011年08月16日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-5654418

summation

[Summation:191507] FRS2 (also known as FRS alpha is activated through tyrosine...

Referrals

(replacementInstances)

[Deleted:5655568] Deletion of instance: 190353

(normalReaction)

[Reaction:R-HSA-5655284] Activated FGFR4 mutants phosphorylate FRS2

(hasEvent)

[Pathway:R-HSA-5654712] FRS-mediated FGFR4 signaling

(precedingEvent)

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