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Go!
Schema
>
CandidateSet
>
Entries
MyD88 variants [cytosol]
Show undefined attributes
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compartment
[Compartment:70101] cytosol
componentOf
[Complex:R-HSA-9037690] MyD88 variant:TLR5:bacterial flagellin [plasma membrane] - Homo sapiens
[Complex:R-HSA-9037690] MyD88 variant:TLR5:bacterial flagellin [plasma membrane] - Homo sapiens
[Complex:R-HSA-9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] - Homo sapiens
[Complex:R-HSA-9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] - Homo sapiens
consumedByEvent
[FailedReaction:R-HSA-5602316] Defective MyD88 does not oligomerize within the complex of activated TLR5 - Homo sapiens
[FailedReaction:R-HSA-5602316] Defective MyD88 does not oligomerize within the complex of activated TLR5 - Homo sapiens
[FailedReaction:R-HSA-5602316] Defective MyD88 does not oligomerize within the complex of activated TLR5 - Homo sapiens
[FailedReaction:R-HSA-5602316] Defective MyD88 does not oligomerize within the complex of activated TLR5 - Homo sapiens
[FailedReaction:R-HSA-5602383] Defective MyD88 does not oligomerize within the activated TLR2/4 complex - Homo sapiens
[FailedReaction:R-HSA-5602383] Defective MyD88 does not oligomerize within the activated TLR2/4 complex - Homo sapiens
[FailedReaction:R-HSA-5602383] Defective MyD88 does not oligomerize within the activated TLR2/4 complex - Homo sapiens
[FailedReaction:R-HSA-5602383] Defective MyD88 does not oligomerize within the activated TLR2/4 complex - Homo sapiens
created
[InstanceEdit:5602721] Shamovsky, Veronica, 2014年06月24日
crossReference
[DatabaseIdentifier:11945161] Mondo:0003778
dbId
5602754
disease
[Disease:5228860] primary immunodeficiency disease
displayName
MyD88 variants [cytosol]
hasCandidate
[EntityWithAccessionedSequence:R-HSA-5602521] MyD88 S34Y [cytosol] - Homo sapiens
[EntityWithAccessionedSequence:R-HSA-5602598] MyD88 E65del [cytosol] - Homo sapiens
hasMember
[EntityWithAccessionedSequence:R-HSA-5602451] MyD88 E52del [cytosol] - Homo sapiens
[EntityWithAccessionedSequence:R-HSA-5602612] MyD88 L93P [cytosol] - Homo sapiens
inDisease
true
maxDepth
2
name
MyD88 variants
schemaClass
CandidateSet
species
[Species:48887] Homo sapiens
stId
R-HSA-5602754
Referrals
(input)
[FailedReaction:R-HSA-5602316] Defective MyD88 does not oligomerize within the complex of activated TLR5
[FailedReaction:R-HSA-5602383] Defective MyD88 does not oligomerize within the activated TLR2/4 complex
(hasComponent)
[Complex:R-HSA-9037690] MyD88 variant:TLR5:bacterial flagellin [plasma membrane]
[Complex:R-HSA-9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane]
(diseaseEntity)
[EntityFunctionalStatus:5602376] loss_of_function of MyD88 variants [cytosol]
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