Defective MyD88 does not oligomerize within the activated TLR2/4 complex

authored
category transition
compartment
created [InstanceEdit:5602721] Shamovsky, Veronica, 2014年06月24日
crossReference
dbId 5602383
disease
displayName Defective MyD88 does not oligomerize within the activated TLR2/4 complex
edited
entityFunctionalStatus
eventOf
input
isChimeric false
isInDisease true
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
  • Defective MyD88 does not oligomerize within the activated TLR2/4 complex
normalReaction [Reaction:R-HSA-937079] MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88
relatedSpecies
releaseDate 2015年03月19日
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass FailedReaction
species
stId R-HSA-5602383
summation
systematicName Defective MyD88 variants do not bind IRAK4, Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer
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