glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9643295] delta1-pyrroline-5-carboxylate synthetase activity of P5CS dimers [mitochondrial inner membrane] Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition
category transition
compartment
created [InstanceEdit:508032] D'Eustachio, P, 2010年02月10日
crossReference
dbId 508040
displayName glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]
edited
eventOf
followingEvent
input
isChimeric false
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
  • glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]
  • ATP + H(+) + L-glutamate + NADPH => ADP + L-glutamate 5-semialdehyde + NADP(+) + phosphate
orthologousEvent
output
precedingEvent
releaseDate 2010年03月16日
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-508040
summation
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