Reactome Pathway Database

Schema > Complex > Entries

PDPK1:p-S473-AKT1 E17K mutant:PIP2 [plasma membrane] Show undefined attributes

catalystActivities

[CatalystActivity:2243940] protein serine/threonine kinase activity of PDPK1:p-S473-AKT1 E17K mutant:PIP2 [plasma membrane]

compartment

[Compartment:876] plasma membrane

consumedByEvent

[Reaction:R-HSA-2243942] PDPK1 phosphorylates AKT1 E17K mutant - Homo sapiens

created [InstanceEdit:2243934] Orlic-Milacic, M, 2012年05月09日

crossReference

dbId 2243941

disease

displayName PDPK1:p-S473-AKT1 E17K mutant:PIP2 [plasma membrane]

hasComponent

inDisease true

isChimeric false

maxDepth 3

name

PDPK1:p-S473-AKT1 E17K mutant:PIP2

producedByEvent

[Reaction:R-HSA-2243937] PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1 - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-2243941

Referrals

(output)

[Reaction:R-HSA-2243937] PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1

(input)

[Reaction:R-HSA-2243942] PDPK1 phosphorylates AKT1 E17K mutant

(diseaseEntity)

[EntityFunctionalStatus:3080614] gain_of_function of PDPK1:p-S473-AKT1 E17K mutant:PIP2 [plasma membrane]

(physicalEntity)

[CatalystActivity:2243940] protein serine/threonine kinase activity of PDPK1:p-S473-AKT1 E17K mutant:PIP2 [plasma membrane]

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