Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

DNMT1 [nucleoplasm] Show undefined attributes

compartment

[Compartment:7660] nucleoplasm

componentOf

consumedByEvent

[Reaction:R-HSA-4655431] SUMOyation of DNMT1 with SUMO1 - Homo sapiens
[Reaction:R-HSA-9851071] STAT3, DNMT1 and HDAC1 bind PTPN6 gene - Homo sapiens
[Reaction:R-HSA-9851058] AcK685 p-Y705, S727 STAT3 dimer and DNMT1 bind IL2RG gene - Homo sapiens
[Reaction:R-HSA-5334160] UHRF1:Chromatin binds DNMT1 - Homo sapiens
[Reaction:R-HSA-427409] Nucleolar Remodelling Complex (NoRC) binds intergenic region of rDNA - Homo sapiens

created [InstanceEdit:212086] May, B, Gopinathrao, G, 2008年02月08日 19:50:06

dbId 212181

displayName DNMT1 [nucleoplasm]

endCoordinate 1616

inDisease false

inferredTo

maxDepth 1

memberOf

[DefinedSet:R-HSA-212315] DNMT1,3A,3B [nucleoplasm] - Homo sapiens

modified [InstanceEdit:3132750] Wu, G, 2013年02月13日

name

DNMT1

negativelyRegulates

[NegativeGeneExpressionRegulation:9850965] Negative gene expression regulation by 'DNMT1 [nucleoplasm]'

producedByEvent

[BlackBoxEvent:R-HSA-9851145] Translation of DNMT1 mRNA is repressed by miR-21 - Homo sapiens

referenceEntity [ReferenceGeneProduct:uniprot:P26358] UniProt:P26358 DNMT1

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-212181

startCoordinate 1

Referrals

(input)

(hasComponent)

(activeUnit)

(hasMember)

[DefinedSet:R-HSA-212315] DNMT1,3A,3B [nucleoplasm]

(regulator)

[NegativeGeneExpressionRegulation:9850965] Negative gene expression regulation by 'DNMT1 [nucleoplasm]'

(output)

[BlackBoxEvent:R-HSA-9851145] Translation of DNMT1 mRNA is repressed by miR-21

(requiredInputComponent)

[Reaction:R-HSA-9817458] TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3

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