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Schema
>
BlackBoxEvent
>
Entries
NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein
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authored
[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008年05月23日
category
omitted
compartment
[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created
[InstanceEdit:211351] D'Eustachio, P, 2008年02月01日 22:29:46
dbId
211346
displayName
NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein
edited
[InstanceEdit:349681] D'Eustachio, P, 2008年05月12日 21:43:33
eventOf
[Pathway:R-HSA-210745] Regulation of gene expression in beta cells - Homo sapiens
followingEvent
[Reaction:R-HSA-70420] HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P - Homo sapiens
inferredFrom
[BlackBoxEvent:R-MMU-186510] NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein - Mus musculus
input
[EntityWithAccessionedSequence:R-HSA-9606120] GCK gene [nucleoplasm]
isInDisease
false
isInferred
true
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein
output
[EntityWithAccessionedSequence:R-HSA-450094] GCK [cytosol]
precedingEvent
[BlackBoxEvent:R-HSA-211272] FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein - Homo sapiens
regulatedBy
[PositiveGeneExpressionRegulation:R-HSA-633894] Positive gene expression regulation by 'PDX1 [nucleoplasm]'
[PositiveGeneExpressionRegulation:R-HSA-633895] Positive gene expression regulation by 'NEUROD1 [nucleoplasm]'
releaseDate
2008年06月30日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:349683] Jensen, J, 2008年05月12日 21:46:53
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-211346
summation
[Summation:211347] The glucokinase (GCK) gene is transcribed and its mRNA is tr...
updateTrackers
[UpdateTracker:9779526] Update Tracker - [BlackBoxEvent:211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - v65:[addInput]
[UpdateTracker:9790579] Update Tracker - [BlackBoxEvent:211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - v33:[addRegulator]
[UpdateTracker:9790884] Update Tracker - [BlackBoxEvent:211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - v32:[add_removeOutput]
Referrals
(updatedInstance)
[UpdateTracker:9779526] Update Tracker - [BlackBoxEvent:211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - v65:[addInput]
[UpdateTracker:9790579] Update Tracker - [BlackBoxEvent:211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - v33:[addRegulator]
[UpdateTracker:9790884] Update Tracker - [BlackBoxEvent:211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - v32:[add_removeOutput]
(hasEvent)
[Pathway:R-HSA-210745] Regulation of gene expression in beta cells
(precedingEvent)
[Reaction:R-HSA-70420] HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P
(inferredTo)
[BlackBoxEvent:R-MMU-186510] NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein
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