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Schema
>
BlackBoxEvent
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Entries
NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein
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authored
[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008年05月23日
category
omitted
compartment
[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created
[InstanceEdit:186665] Tello-Ruiz, MK, 2006年08月14日 15:25:20
dbId
186510
deleted
[Deleted:8863072] Deletion of instance: 186588
displayName
NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein
edited
[InstanceEdit:190295] Tello-Ruiz, MK, 2006年12月19日 19:02:30
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:187472] BETA2 activates transcription from the upstream glucokinase gene promoter in islet beta-cells and gut endocrine cells
[LiteratureReference:187269] Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2.
[LiteratureReference:186720] Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding.
[LiteratureReference:187315] The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein
orthologousEvent
[BlackBoxEvent:R-HSA-211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - Homo sapiens
output
[DefinedSet:R-MMU-211356] Glucokinase [cytosol]
regulatedBy
[PositiveRegulation:R-MMU-189728] Positive regulation by 'ipf1/pdx1 [nucleoplasm]'
[PositiveRegulation:R-MMU-189741] Positive regulation by 'NeuroD1 [nucleoplasm]'
releaseDate
2008年06月30日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:349683] Jensen, J, 2008年05月12日 21:46:53
schemaClass
BlackBoxEvent
species
[Species:48892] Mus musculus
stId
R-MMU-186510
summation
[Summation:186522] NeuroD1 binds to control sequences of the mouse GK gene in v...
updateTrackers
[UpdateTracker:9783245] Update Tracker - [BlackBoxEvent:186510] NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein - v57:[addLiteratureReference, addRegulator, modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9783245] Update Tracker - [BlackBoxEvent:186510] NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein - v57:[addLiteratureReference, addRegulator, modifyText]
(replacementInstances)
[Deleted:8863072] Deletion of instance: 186588
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