Reactome Pathway Database

Schema > Complex > Entries

FGFR2b mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane] Show undefined attributes

catalystActivities

[CatalystActivity:2033450] protein tyrosine kinase activity of FGFR2b mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane]

compartment

[Compartment:876] plasma membrane

consumedByEvent

[Reaction:R-HSA-2033488] Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding - Homo sapiens

created [InstanceEdit:2065928] Rothfels, K, 2012年01月24日

crossReference

dbId 2065929

disease

displayName FGFR2b mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane]

hasComponent

inDisease true

includedLocation

[Compartment:984] extracellular region

isChimeric false

maxDepth 4

memberOf

[DefinedSet:R-HSA-2077401] FGFR2 point mutant dimers [plasma membrane] - Homo sapiens

name

FGFR2b mutant dimers with enhanced ligand-binding bound to FGFs

producedByEvent

[Reaction:R-HSA-2033474] FGFR2b mutants bind an expanded range of ligands - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-2065929

Referrals

(hasMember)

[DefinedSet:R-HSA-2077401] FGFR2 point mutant dimers [plasma membrane]

(input)

[Reaction:R-HSA-2033488] Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding

(diseaseEntity)

[EntityFunctionalStatus:5654454] gain_of_function of FGFR2b mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane]

(physicalEntity)

[CatalystActivity:2033450] protein tyrosine kinase activity of FGFR2b mutant dimers with enhanced ligand-binding bound to FGFs [plasma membrane]

(output)

[Reaction:R-HSA-2033474] FGFR2b mutants bind an expanded range of ligands

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