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Entries
Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha
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authored
[InstanceEdit:201620] Schulze-Osthoff, K, 2007年09月03日 07:52:18
catalystActivity
[CatalystActivity:114327] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:201633] Matthews, L, 2007年09月03日 08:38:43
dbId
201640
displayName
Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha
edited
[InstanceEdit:201589] Matthews, L, 2007年09月03日 07:38:20
[InstanceEdit:201989] Matthews, L, 2007年10月09日 13:44:38
[InstanceEdit:202801] Matthews, L, 2007年11月11日 23:40:56
eventOf
[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins - Homo sapiens
input
[EntityWithAccessionedSequence:R-HSA-2530516] FNTA(2-379) [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:202868] Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis
maxDepth
1
modified
[InstanceEdit:10867632] Weiser, Joel, 2025年08月27日
name
Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha
orthologousEvent
[Reaction:R-CEL-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Caenorhabditis elegans
[Reaction:R-DME-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Drosophila melanogaster
[Reaction:R-GGA-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Gallus gallus
[Reaction:R-XTR-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Xenopus tropicalis
[Reaction:R-DRE-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Danio rerio
[Reaction:R-BTA-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Bos taurus
[Reaction:R-RNO-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Rattus norvegicus
[Reaction:R-MMU-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Mus musculus
output
[EntityWithAccessionedSequence:R-HSA-202869] FNTA(1-59) [cytosol]
[EntityWithAccessionedSequence:R-HSA-202872] FNTA(59-379) [cytosol]
precedingEvent
[Reaction:R-HSA-114252] Cleavage of Procaspase-3 by the apoptosome - Homo sapiens
[Reaction:R-HSA-114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - Homo sapiens
[Reaction:R-HSA-418845] Activation of caspase-3 - Homo sapiens
releaseDate
2006年08月02日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:204051] Ranganathan, S, 2007年11月23日 00:10:26
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-201640
summation
[Summation:202849] Farnesyltransferase/geranyl-geranyltransferase catalyzes th...
updateTrackers
[UpdateTracker:9787556] Update Tracker - [Reaction:201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - v44:[removeInput]
[UpdateTracker:9787470] Update Tracker - [Reaction:201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - v45:[addInput]
Referrals
(updatedInstance)
[UpdateTracker:9787556] Update Tracker - [Reaction:201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - v44:[removeInput]
[UpdateTracker:9787470] Update Tracker - [Reaction:201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - v45:[addInput]
(hasEvent)
[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins
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