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Entries
Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3
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authored
[InstanceEdit:111451] Alnemri, E, 2004年02月17日 00:23:30
category
dissociation
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:111451] Alnemri, E, 2004年02月17日 00:23:30
dbId
114419
displayName
Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3
edited
[InstanceEdit:9627414] Shamovsky, Veronica, 2018年11月02日
eventOf
[Pathway:R-HSA-111464] SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes - Homo sapiens
followingEvent
[Reaction:R-HSA-350651] Caspase-mediated cleavage of MASK - Homo sapiens
[Reaction:R-HSA-201630] Caspase-mediated cleavage of Acinus - Homo sapiens
[Reaction:R-HSA-202960] Caspase mediated cleavage of C-IAP1 - Homo sapiens
[Reaction:R-HSA-351849] Caspase-mediated cleavage of Etk - Homo sapiens
[Reaction:R-HSA-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - Homo sapiens
[Reaction:R-HSA-212552] Caspase 3-mediated cleavage of PKC delta - Homo sapiens
[Reaction:R-HSA-201611] Caspase-mediated cleavage of Rock-1 - Homo sapiens
[Reaction:R-HSA-201631] Caspase-mediated cleavage of Desmoglein 3 - Homo sapiens
[Reaction:R-HSA-202969] Caspase mediated cleavage of beta-catenin - Homo sapiens
[Reaction:R-HSA-202917] Caspase-mediated cleavage of Desmoglein 1 - Homo sapiens
[Reaction:R-HSA-351877] Caspase-mediated cleavage of Desmoglein 2 - Homo sapiens
[Reaction:R-HSA-201608] Caspase-mediated cleavage of alpha adducin - Homo sapiens
[Reaction:R-HSA-202966] Caspase mediated cleavage of HIP-55 - Homo sapiens
[Reaction:R-HSA-202967] Caspase mediated cleavage of alpha-II-Fodrin - Homo sapiens
[Reaction:R-HSA-201603] Caspase-mediated cleavage of PKC theta - Homo sapiens
[Reaction:R-HSA-202947] Caspase mediated cleavage of APC - Homo sapiens
[Reaction:R-HSA-211219] Translocation of caspase-3 to the nucleus - Homo sapiens
[Reaction:R-HSA-211651] Cleavage of PAK-2 at 212 - Homo sapiens
[Reaction:R-HSA-201629] Caspase-mediated cleavage of Tau - Homo sapiens
[Reaction:R-HSA-201622] Caspase-mediated cleavage of gelsolin - Homo sapiens
[Reaction:R-HSA-201639] Caspase-mediated cleavage of GAS2 - Homo sapiens
[Reaction:R-HSA-201628] Caspase-mediated cleavage of vimentin at DSVD (85) - Homo sapiens
inferredFrom
[Reaction:R-HSA-114392] Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 - Homo sapiens
input
[Complex:R-HSA-114305] DIABLO:XIAP:Caspase-3 [cytosol]
isInDisease
false
isInferred
true
literatureReference
[LiteratureReference:3148619] XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3
output
[Complex:R-HSA-350870] Caspase-3 [cytosol]
[Complex:R-HSA-9627391] DIABLO dimer:XIAP [cytosol]
precedingEvent
[Reaction:R-HSA-114306] SMAC binds XIAP:Caspase-3 - Homo sapiens
releaseDate
2004年10月27日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9627969] Matthews, Lisa, 2018年11月05日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-114419
summation
[Summation:178685] The linker region preceding BIR2 of XIAP is responsible for ...
updateTrackers
[UpdateTracker:9778839] Update Tracker - [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - v67:[add_removeOutput, modifyText]
[UpdateTracker:9787526] Update Tracker - [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9783910] Update Tracker - [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - v55:[add_removeOutput]
Referrals
(updatedInstance)
[UpdateTracker:9778839] Update Tracker - [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - v67:[add_removeOutput, modifyText]
[UpdateTracker:9787526] Update Tracker - [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9783910] Update Tracker - [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - v55:[add_removeOutput]
(hasEvent)
[Pathway:R-HSA-111464] SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
(precedingEvent)
[Reaction:R-HSA-211651] Cleavage of PAK-2 at 212
[Reaction:R-HSA-350651] Caspase-mediated cleavage of MASK
[Reaction:R-HSA-201630] Caspase-mediated cleavage of Acinus
[Reaction:R-HSA-202960] Caspase mediated cleavage of C-IAP1
[Reaction:R-HSA-351849] Caspase-mediated cleavage of Etk
[Reaction:R-HSA-201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha
[Reaction:R-HSA-212552] Caspase 3-mediated cleavage of PKC delta
[Reaction:R-HSA-201611] Caspase-mediated cleavage of Rock-1
[Reaction:R-HSA-201631] Caspase-mediated cleavage of Desmoglein 3
[Reaction:R-HSA-202969] Caspase mediated cleavage of beta-catenin
[Reaction:R-HSA-202917] Caspase-mediated cleavage of Desmoglein 1
[Reaction:R-HSA-351877] Caspase-mediated cleavage of Desmoglein 2
[Reaction:R-HSA-201628] Caspase-mediated cleavage of vimentin at DSVD (85)
[Reaction:R-HSA-201629] Caspase-mediated cleavage of Tau
[Reaction:R-HSA-201608] Caspase-mediated cleavage of alpha adducin
[Reaction:R-HSA-201622] Caspase-mediated cleavage of gelsolin
[Reaction:R-HSA-202966] Caspase mediated cleavage of HIP-55
[Reaction:R-HSA-201639] Caspase-mediated cleavage of GAS2
[Reaction:R-HSA-202967] Caspase mediated cleavage of alpha-II-Fodrin
[Reaction:R-HSA-201603] Caspase-mediated cleavage of PKC theta
[Reaction:R-HSA-202947] Caspase mediated cleavage of APC
[Reaction:R-HSA-211219] Translocation of caspase-3 to the nucleus
(inferredTo)
[Reaction:R-HSA-114392] Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7
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