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Schema
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Reaction
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Entries
Caspase-mediated cleavage of GAS2
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authored
[InstanceEdit:201620] Schulze-Osthoff, K, 2007年09月03日 07:52:18
catalystActivity
[CatalystActivity:202853] cysteine-type endopeptidase activity of Caspase-3, Caspase-7 [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:201633] Matthews, L, 2007年09月03日 08:38:43
dbId
201639
displayName
Caspase-mediated cleavage of GAS2
edited
[InstanceEdit:201589] Matthews, L, 2007年09月03日 07:38:20
[InstanceEdit:201989] Matthews, L, 2007年10月09日 13:44:38
[InstanceEdit:202801] Matthews, L, 2007年11月11日 23:40:56
eventOf
[Pathway:R-HSA-264870] Caspase-mediated cleavage of cytoskeletal proteins - Homo sapiens
input
[EntityWithAccessionedSequence:R-HSA-201614] GAS2 [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:202842] Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases
[LiteratureReference:202885] Caspase-3 and caspase-7 but not caspase-6 cleave Gas2 in vitro: implications for microfilament reorganization during apoptosis
maxDepth
1
modified
[InstanceEdit:10680101] Weiser, Joel, 2025年08月27日
name
Caspase-mediated cleavage of GAS2
orthologousEvent
[Reaction:R-GGA-201639] Caspase-mediated cleavage of GAS2 - Gallus gallus
[Reaction:R-XTR-201639] Caspase-mediated cleavage of GAS2 - Xenopus tropicalis
[Reaction:R-SSC-201639] Caspase-mediated cleavage of GAS2 - Sus scrofa
[Reaction:R-BTA-201639] Caspase-mediated cleavage of GAS2 - Bos taurus
[Reaction:R-CFA-201639] Caspase-mediated cleavage of GAS2 - Canis familiaris
[Reaction:R-RNO-201639] Caspase-mediated cleavage of GAS2 - Rattus norvegicus
[Reaction:R-MMU-201639] Caspase-mediated cleavage of GAS2 - Mus musculus
output
[EntityWithAccessionedSequence:R-HSA-202833] GAS2(1-279) [cytosol]
[EntityWithAccessionedSequence:R-HSA-202887] GAS2(280-313) [cytosol]
precedingEvent
[Reaction:R-HSA-114252] Cleavage of Procaspase-3 by the apoptosome - Homo sapiens
[Reaction:R-HSA-114261] Cleavage of Procaspase-7 by the apoptosome - Homo sapiens
[Reaction:R-HSA-114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - Homo sapiens
[Reaction:R-HSA-114392] Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 - Homo sapiens
[Reaction:R-HSA-418845] Activation of caspase-3 - Homo sapiens
releaseDate
2005年09月26日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:204051] Ranganathan, S, 2007年11月23日 00:10:26
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-201639
summation
[Summation:202884] Cleavage of Gas2 during apoptosis is associated with changes...
updateTrackers
[UpdateTracker:9782175] Update Tracker - [Reaction:201639] Caspase-mediated cleavage of GAS2 - v59:[add_removeLiteratureReference]
Referrals
(updatedInstance)
[UpdateTracker:9782175] Update Tracker - [Reaction:201639] Caspase-mediated cleavage of GAS2 - v59:[add_removeLiteratureReference]
(hasEvent)
[Pathway:R-HSA-264870] Caspase-mediated cleavage of cytoskeletal proteins
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