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Entries
25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA
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authored
[InstanceEdit:191331] Jassal, Bijay, 2007年01月19日
catalystActivity
[CatalystActivity:192336] acyl-CoA oxidase activity of ACOX2:FAD [peroxisomal matrix]
category
transition
compartment
[Compartment:17951] peroxisomal matrix
created
[InstanceEdit:193476] D'Eustachio, P, 2007年02月19日 17:36:33
dbId
193369
displayName
25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA
edited
[InstanceEdit:193475] D'Eustachio, P, 2007年02月17日 19:40:28
eventOf
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Homo sapiens
followingEvent
[Reaction:R-HSA-193535] 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Homo sapiens
input
[SimpleEntity:R-ALL-193442] 25(S) DHCA-CoA [peroxisomal matrix]
[SimpleEntity:R-ALL-113535] O2 [peroxisomal matrix]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:192346] Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome
[LiteratureReference:193409] The CoA esters of 2-methyl-branched chain fatty acids and of the bile acid intermediates di- and trihydroxycoprostanic acids are oxidized by one single peroxisomal branched chain acyl-CoA oxidase in human liver and kidney
maxDepth
1
modified
[InstanceEdit:10948619] Weiser, Joel, 2025年08月27日
name
25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA
25(S) DHCA-CoA + O2 => 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA + H2O2
orthologousEvent
[Reaction:R-DDI-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Dictyostelium discoideum
[Reaction:R-CEL-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Caenorhabditis elegans
[Reaction:R-DME-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Drosophila melanogaster
[Reaction:R-GGA-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Gallus gallus
[Reaction:R-XTR-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Xenopus tropicalis
[Reaction:R-SSC-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Sus scrofa
[Reaction:R-BTA-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Bos taurus
[Reaction:R-CFA-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Canis familiaris
[Reaction:R-RNO-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Rattus norvegicus
[Reaction:R-MMU-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Mus musculus
output
[SimpleEntity:R-ALL-193459] 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA [peroxisomal matrix]
[SimpleEntity:R-ALL-113575] H2O2 [peroxisomal matrix]
precedingEvent
[Reaction:R-HSA-193452] Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA - Homo sapiens
releaseDate
2007年05月15日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:197117] D'Eustachio, P, 2007年04月30日 14:43:26
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-193369
summation
[Summation:193468] 25(S) DHCA-CoA and O2 react to form 25(S) 3alpha,7alpha-dihy...
Referrals
(hasEvent)
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(precedingEvent)
[Reaction:R-HSA-193535] 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA
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