Reactome Pathway Database

Schema > Reaction > Entries

25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA Show undefined attributes

catalystActivity

[CatalystActivity:10615168] acyl-CoA oxidase activity of ACOX2:FAD [peroxisomal matrix]

category transition

compartment

[Compartment:17951] peroxisomal matrix

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10615282

displayName 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA

eventOf

[Pathway:R-XTR-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA
25(S) DHCA-CoA + O2 => 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA + H2O2

output

precedingEvent

[Reaction:R-XTR-193452] Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA - Xenopus tropicalis

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-193369

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

(inferredTo)

[Reaction:R-HSA-193369] 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA

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