Reactome Pathway Database

Schema > Reaction > Entries

TGFBR2 phosphorylates TGFBR1 Show undefined attributes

authored

[InstanceEdit:171270] Heldin, CH, Moustakas, A, Huminiecki, L, Jassal, B, 2006年02月02日

catalystActivity

[CatalystActivity:170856] transforming growth factor beta receptor activity, type II of TGFB1:TGFBR2:TGFBR1 [plasma membrane]

category transition

compartment

created [InstanceEdit:170836] Jassal, B, 2006年01月18日 10:19:52

dbId 170843

displayName TGFBR2 phosphorylates TGFBR1

edited

[InstanceEdit:170836] Jassal, B, 2006年01月18日 10:19:52

eventOf

[Pathway:R-HSA-2173789] TGF-beta receptor signaling activates SMADs - Homo sapiens

followingEvent

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

TGFBR2 phosphorylates TGFBR1
Type II receptor phosphorylates type I receptor

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-170846] TGFBR2 recruits TGFBR1 - Homo sapiens

releaseDate 2006年04月24日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-170843

summation

[Summation:176016] Formation of the hetero-tetrameric TGF-beta-1 receptor compl...

updateTrackers

Referrals

(updatedInstance)

(normalReaction)

[FailedReaction:R-HSA-3645780] TGFBR2 KD mutants do not phosphorylate TGFBR1

(precedingEvent)

(hasEvent)

[Pathway:R-HSA-2173789] TGF-beta receptor signaling activates SMADs

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