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Schema
>
Complex
>
Entries
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane]
Show undefined attributes
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compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-HSA-2134534] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] - Homo sapiens
[Complex:R-NUL-2161166] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-Pard6a:RHOA [cell junction] - Homo sapiens
consumedByEvent
[Reaction:R-NUL-2169036] Smad7:SMURF1 binds phosphorylated TGFBR1 - Homo sapiens
[Reaction:R-NUL-2169043] Smad7:SMURF2 binds phosphorylated TGFBR1 - Homo sapiens
[Reaction:R-HSA-173512] I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) - Homo sapiens
[Reaction:R-HSA-170835] An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 - Homo sapiens
[Reaction:R-HSA-173483] BAMBI interferes with the interaction of type I receptor with type II receptor - Homo sapiens
[Reaction:R-NUL-2176431] Smad7 recruits NEDD4L to activated TGF-beta receptor complex - Homo sapiens
[Reaction:R-HSA-178218] SMAD7:SMURF complex binds to phosphorylated TGFBR1 - Homo sapiens
[Reaction:R-NUL-2128982] Strap binds phosphorylated TGF-beta receptor complex - Homo sapiens
[Reaction:R-HSA-2127562] STRAP binds phosphorylated TGF-beta receptor complex - Homo sapiens
created
[InstanceEdit:170836] Jassal, B, 2006年01月18日 10:19:52
dbId
170841
displayName
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane]
hasComponent
[Complex:R-HSA-170852] Dimeric TGFB1 [extracellular region]
[Complex:R-HSA-170863] p-TGFBR1 [plasma membrane]
[Complex:R-HSA-170866] TGFBR2 homodimer [plasma membrane]
inDisease
false
includedLocation
[Compartment:984] extracellular region
inferredTo
[Complex:R-MMU-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Mus musculus
[Complex:R-RNO-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Rattus norvegicus
[Complex:R-CFA-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Canis familiaris
[Complex:R-BTA-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Bos taurus
[Complex:R-SSC-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Sus scrofa
[Complex:R-DRE-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Danio rerio
[Complex:R-XTR-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Xenopus tropicalis
[Complex:R-GGA-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Gallus gallus
[Complex:R-DME-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Drosophila melanogaster
[Complex:R-CEL-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Caenorhabditis elegans
maxDepth
3
modified
[InstanceEdit:2167891] Orlic-Milacic, M, 2012年03月22日
name
TGFB1:TGFBR2:p-TGFBR1
TGF-beta 1:type II receptor:Phospho-type I receptor complex
producedByEvent
[Reaction:R-HSA-170843] TGFBR2 phosphorylates TGFBR1 - Homo sapiens
schemaClass
Complex
species
[Species:48887] Homo sapiens
stId
R-HSA-170841
updateTrackers
[UpdateTracker:9871747] Update Tracker - [Complex:170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - v41:[modifyName, updateContainedComponent]
[UpdateTracker:9870702] Update Tracker - [Complex:170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - v38:[addName, updateContainedComponent]
Referrals
(updatedInstance)
[UpdateTracker:9871747] Update Tracker - [Complex:170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - v41:[modifyName, updateContainedComponent]
[UpdateTracker:9870702] Update Tracker - [Complex:170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - v38:[addName, updateContainedComponent]
(normalEntity)
[EntityFunctionalStatus:3656519] loss_of_function of TGFB1:TGFBR2:p-TGFBR1 KD Mutants [plasma membrane]
(hasComponent)
[Complex:R-NUL-2161166] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-Pard6a:RHOA [cell junction]
[Complex:R-HSA-2134534] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction]
[Complex:R-NUL-2176425] TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-Smad7 [plasma membrane]
[Complex:R-HSA-173509] TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane]
[Complex:R-NUL-2176429] TGFB1:TGFBR2:p-TGFBR1:Smad7:NEDD4L [plasma membrane]
[Complex:R-NUL-2169037] TGFB1:TGFBR2:p-TGFBR1:Smad7:SMURF1 [plasma membrane]
[Complex:R-NUL-2169039] TGFB1:TGFBR2:p-TGFBR1:Smad7:SMURF2 [plasma membrane]
[Complex:R-HSA-2169025] TGFB1:TGFBR2:p-TGFBR1:SMAD7:SMURF/NEDD4L [plasma membrane]
[Complex:R-NUL-2128981] TGFB1:TGFBR2:p-TGFBR1:Strap [plasma membrane]
[Complex:R-HSA-2127564] TGFB1:p-TGFBR:STRAP [plasma membrane]
[Complex:R-HSA-173476] TGFB1: p-TGFBR: I-SMAD7 [plasma membrane]
(input)
[Reaction:R-HSA-173483] BAMBI interferes with the interaction of type I receptor with type II receptor
[Reaction:R-NUL-2176431] Smad7 recruits NEDD4L to activated TGF-beta receptor complex
[Reaction:R-NUL-2169036] Smad7:SMURF1 binds phosphorylated TGFBR1
[Reaction:R-NUL-2169043] Smad7:SMURF2 binds phosphorylated TGFBR1
[Reaction:R-HSA-178218] SMAD7:SMURF complex binds to phosphorylated TGFBR1
[Reaction:R-NUL-2128982] Strap binds phosphorylated TGF-beta receptor complex
[Reaction:R-HSA-2127562] STRAP binds phosphorylated TGF-beta receptor complex
[Reaction:R-HSA-173512] I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1)
[Reaction:R-HSA-170835] An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3
(output)
[Reaction:R-HSA-170843] TGFBR2 phosphorylates TGFBR1
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