Reactome Pathway Database

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Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP Show undefined attributes

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authored

[InstanceEdit:165064] Matthews, L, Rice, AP, 2005年07月27日 00:00:00

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:165042] Matthews, L, 2005年07月26日 23:04:06

crossReference

[DatabaseIdentifier:11944912] Mondo:0005109

dbId 165034

deleted

[Deleted:193234] Deletion of instance: 165030

disease

[Disease:1660559] Human immunodeficiency virus infectious disease

displayName Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP

edited

[InstanceEdit:182365] Matthews, L, 2006年07月07日 14:08:37

eventOf

[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA - Homo sapiens

followingEvent

[Reaction:R-HSA-165043] Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC - Homo sapiens

input

isInDisease true

isInferred false

literatureReference

[LiteratureReference:167644] The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP

output

[Complex:R-HSA-165537] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP [nucleoplasm]

precedingEvent

relatedSpecies

[Species:164493] Human immunodeficiency virus 1

releaseDate 2005年04月11日

requiredInputComponent

[EntityWithAccessionedSequence:R-HSA-165529] XPO1 [nucleoplasm] - Homo sapiens

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:192365] Kumar, A, 2007年01月31日 22:47:49

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-165034

summation

[Summation:169716] RanGTP binds to a preformed Rev-CRM1 complex.

Referrals

(replacementInstances)

[Deleted:193234] Deletion of instance: 165030

(hasEvent)

[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA

(precedingEvent)

[Reaction:R-HSA-165043] Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC

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