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Autocatalytic activation of bound proMMP2 Show undefined attributes

authored

[InstanceEdit:1592294] Jupe, S, 2011年09月09日

catalystActivity

[CatalystActivity:1604363] serine-type endopeptidase activity of MMP14:TIMP2:MMP2 intermediate form [plasma membrane]

category transition

compartment

created [InstanceEdit:1604374] Jupe, S, 2011年09月15日

dbId 1604368

displayName Autocatalytic activation of bound proMMP2

edited

[InstanceEdit:2129374] Jupe, S, 2012年02月21日

eventOf

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases - Homo sapiens

input

[Complex:R-HSA-1604373] MMP14:TIMP2:MMP2 intermediate form [plasma membrane]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Autocatalytic activation of bound proMMP2

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-1604360] Initial activation of proMMP2 by MMP14 - Homo sapiens

releaseDate 2012年03月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-1604368

summation

[Summation:1604356] Cleavage of the Asn66-Leu67 bond of MMP2 activates it suffic...

Referrals

(hasEvent)

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases

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