Reactome Pathway Database

Schema > BlackBoxEvent > Entries

Activation of proMMP8 Show undefined attributes

authored

[InstanceEdit:1592294] Jupe, S, 2011年09月09日

catalystActivity

[CatalystActivity:2127618] serine-type endopeptidase activity of proMMP8 initial activators [extracellular region]

category omitted

compartment

[Compartment:984] extracellular region

created [InstanceEdit:1592294] Jupe, S, 2011年09月09日

dbId 1592398

displayName Activation of proMMP8

edited

[InstanceEdit:2129374] Jupe, S, 2012年02月21日

eventOf

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-1604708] MMP8(21-467) [extracellular region]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Activation of proMMP8

orthologousEvent

output

[EntityWithAccessionedSequence:R-HSA-1442475] MMP8 [extracellular region]

precedingEvent

[BlackBoxEvent:R-HSA-5625883] PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 - Homo sapiens

releaseDate 2012年03月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-1592398

summation

[Summation:1592341] proMMP8 is activated by tissue kallikrein, leukocyte elastas...

Referrals

(hasEvent)

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases

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