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Entries
PI is hydrolyzed to 1-acyl LPI by PLA2[12]
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authored
[InstanceEdit:1602345] Williams, MG, 2011年09月14日
catalystActivity
[CatalystActivity:1524144] phospholipase A2 activity of PLA2(12) [endoplasmic reticulum membrane]
category
transition
compartment
[Compartment:12045] endoplasmic reticulum membrane
[Compartment:70101] cytosol
created
[InstanceEdit:1482800] Williams, MG, 2011年08月12日
dbId
1482868
displayName
PI is hydrolyzed to 1-acyl LPI by PLA2[12]
edited
[InstanceEdit:1482514] Williams, MG, 2011年08月12日
eventOf
[Pathway:R-HSA-1482922] Acyl chain remodelling of PI - Homo sapiens
followingEvent
[Reaction:R-HSA-1482598] 1-acyl LPI is acylated to PI by MBOAT7 - Homo sapiens
input
[SimpleEntity:R-ALL-29356] H2O [cytosol]
[SimpleEntity:R-ALL-426639] PI [endoplasmic reticulum membrane]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1482657] Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2
[LiteratureReference:1482664] Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
PI is hydrolyzed to 1-acyl LPI by PLA2[12]
orthologousEvent
[Reaction:R-GGA-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Gallus gallus
[Reaction:R-RNO-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Rattus norvegicus
[Reaction:R-MMU-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Mus musculus
[Reaction:R-SCE-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Saccharomyces cerevisiae
[Reaction:R-SPO-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Schizosaccharomyces pombe
[Reaction:R-DRE-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Danio rerio
[Reaction:R-SSC-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Sus scrofa
[Reaction:R-CEL-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Caenorhabditis elegans
[Reaction:R-DME-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Drosophila melanogaster
[Reaction:R-XTR-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Xenopus tropicalis
[Reaction:R-BTA-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Bos taurus
output
[SimpleEntity:R-ALL-1498733] 1-acyl LPI [endoplasmic reticulum membrane]
[SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent
[Reaction:R-HSA-1482976] CDP-DAG is converted to PI by CDIPT - Homo sapiens
[Reaction:R-HSA-1482598] 1-acyl LPI is acylated to PI by MBOAT7 - Homo sapiens
[Reaction:R-HSA-1482626] 2-acyl LPI is acylated to PI by MBOAT7 - Homo sapiens
[Reaction:R-HSA-1676124] PI4P is dephosphorylated to PI by SACM1L at the ER membrane - Homo sapiens
releaseDate
2012年06月12日
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-1482868
summation
[Summation:1482832] At the endoplasmic reticulum (ER) membrane, phosphatidylinos...
Referrals
(hasEvent)
[Pathway:R-HSA-1482922] Acyl chain remodelling of PI
(precedingEvent)
[Reaction:R-HSA-1482598] 1-acyl LPI is acylated to PI by MBOAT7
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