Reactome Pathway Database

Schema > Reaction > Entries

PI is hydrolyzed to 1-acyl LPI by PLA2[12] Show undefined attributes

catalystActivity

[CatalystActivity:11013666] phospholipase A2 activity of PLA2(6) [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11013699

displayName PI is hydrolyzed to 1-acyl LPI by PLA2[12]

eventOf

[Pathway:R-SPO-1482922] Acyl chain remodelling of PI - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SPO-1482598] 1-acyl LPI is acylated to PI by MBOAT7 - Schizosaccharomyces pombe

inferredFrom

[Reaction:R-HSA-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12] - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PI is hydrolyzed to 1-acyl LPI by PLA2[12]

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-1482868

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-1482922] Acyl chain remodelling of PI

(precedingEvent)

[Reaction:R-SPO-1482598] 1-acyl LPI is acylated to PI by MBOAT7

(inferredTo)

[Reaction:R-HSA-1482868] PI is hydrolyzed to 1-acyl LPI by PLA2[12]

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