Reactome Pathway Database

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loss_of_function of NVP-TAE684-resistant ALK mutants [plasma membrane] Show undefined attributes

created [InstanceEdit:9717336] Rothfels, Karen, 2021年03月08日

dbId 9717337

diseaseEntity [DefinedSet:R-HSA-9700568] NVP-TAE684-resistant ALK mutants [plasma membrane]

displayName loss_of_function of NVP-TAE684-resistant ALK mutants [plasma membrane]

functionalStatus

[FunctionalStatus:2317386] loss_of_function via missense_variant

modified [InstanceEdit:9757300] Rothfels, Karen, 2021年10月28日

normalEntity [DefinedSet:R-ALL-9699973] type I ALK-binding TKIs [cytosol]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[FailedReaction:R-HSA-9700114] NVP-TAE684-resistant ALK mutants don't bind NVP-TAE684

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