Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
LiteratureReference
>
Entries
The way Wnt works: Components and mechanism
Show undefined attributes
author
[Person:3238033] Saito-Diaz, K
[Person:3237968] Chen, TW
[Person:3238058] Wang, X
[Person:3238048] Thorne, CA
[Person:3238056] Wallace, HA
[Person:3238022] Page-McCaw, A
[Person:3238002] Lee, E
created
[InstanceEdit:3238085] Rothfels, K, 2013年03月27日
dbId
3238089
displayName
The way Wnt works: Components and mechanism
journal
Growth Factors
pages
1-31
pubMedIdentifier
23256519
schemaClass
LiteratureReference
title
The way Wnt works: Components and mechanism
url
http://www.ncbi.nlm.nih.gov/pubmed/23256519
volume
31
year
2013
Referrals
(literatureReference)
[Pathway:R-HSA-4839735] Signaling by AXIN mutants
[Pathway:R-HSA-4839748] Signaling by AMER1 mutants
[Pathway:R-HSA-4839744] Signaling by APC mutants
[FailedReaction:R-HSA-4791278] APC truncation mutants have impaired AXIN binding
[Pathway:R-HSA-4839743] Signaling by CTNNB1 phospho-site mutants
[Pathway:R-HSA-5358752] CTNNB1 T41 mutants aren't phosphorylated
[FailedReaction:R-HSA-4839638] CTNNB1 T41 mutants aren't phosphorylated by GSK3beta
[Pathway:R-HSA-195721] Signaling by WNT
[Pathway:R-HSA-3858494] Beta-catenin independent WNT signaling
[Pathway:R-HSA-201681] TCF dependent signaling in response to WNT
[Pathway:R-HSA-3238698] WNT ligand biogenesis and trafficking
[BlackBoxEvent:R-HSA-5229348] Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes
[Reaction:R-HSA-5229343] AXIN is phosphorylated in the destruction complex
[BlackBoxEvent:R-HSA-5251555] Expression of AXIN1 gene
[BlackBoxEvent:R-HSA-4411365] Transcription of canonical WNT targets is negatively regulated by NLK-dependent phosphorylation of TCF/LEF
[Reaction:R-HSA-8944362] TCF/LEF:CTNNB1 bind canonical WNT target promoters
[BlackBoxEvent:R-HSA-201669] Beta-catenin translocates to the nucleus
[Reaction:R-HSA-201685] Beta-catenin is released from the destruction complex
[Reaction:R-HSA-1458875] WNT binds to FZD and LRP5/6
(author)
[Person:3238058] Wang, X
[Person:3238056] Wallace, HA
[Person:3238022] Page-McCaw, A
[Person:3238002] Lee, E
[Person:3238048] Thorne, CA
[Person:3237968] Chen, TW
[Person:3238033] Saito-Diaz, K
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル