Reactome Pathway Database

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BioModels Database:BIOMD0000000407 Show undefined attributes

created [InstanceEdit:12757879] Weiser, Joel, 2025年08月05日

databaseName BioModels Database

dbId 12757942

displayName BioModels Database:BIOMD0000000407

identifier BIOMD0000000407

referenceDatabase [ReferenceDatabase:12757881] BioModels Database

schemaClass DatabaseIdentifier

url https://www.ebi.ac.uk/biomodels/BIOMD0000000407

Referrals

(crossReference)

[Pathway:R-HSA-209560] NF-kB is activated and signals survival
[Pathway:R-HSA-1169091] Activation of NF-kappaB in B cells
[Pathway:R-HSA-111463] SMAC (DIABLO) binds to IAPs
[Pathway:R-HSA-264870] Caspase-mediated cleavage of cytoskeletal proteins
[Pathway:R-HSA-75893] TNF signaling
[Pathway:R-HSA-75153] Apoptotic execution phase
[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins
[Pathway:R-HSA-3371378] Regulation by c-FLIP
[Pathway:R-HSA-111469] SMAC, XIAP-regulated apoptotic response
[Pathway:R-HSA-5660668] CLEC7A/inflammasome pathway
[Pathway:R-HSA-9693928] Defective RIPK1-mediated regulated necrosis
[Pathway:R-HSA-75157] FasL/ CD95L signaling
[Pathway:R-HSA-933542] TRAF6 mediated NF-kB activation
[Pathway:R-HSA-168927] TICAM1, RIP1-mediated IKK complex recruitment
[Pathway:R-HSA-140534] Caspase activation via Death Receptors in the presence of ligand
[Pathway:R-HSA-111459] Activation of caspases through apoptosome-mediated cleavage
[Pathway:R-HSA-5675482] Regulation of necroptotic cell death
[Pathway:R-HSA-937041] IKK complex recruitment mediated by RIP1
[Pathway:R-HSA-69416] Dimerization of procaspase-8
[Pathway:R-HSA-9013957] TLR3-mediated TICAM1-dependent programmed cell death
[Pathway:R-HSA-1810476] RIP-mediated NFkB activation via ZBP1
[Pathway:R-HSA-933543] NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
[Pathway:R-HSA-5603029] IkBA variant leads to EDA-ID
[Pathway:R-HSA-5218900] CASP8 activity is inhibited
[Pathway:R-HSA-352238] Breakdown of the nuclear lamina
[Pathway:R-HSA-5213460] RIPK1-mediated regulated necrosis
[Pathway:R-HSA-445989] TAK1-dependent IKK and NF-kappa-B activation
[Pathway:R-HSA-9686347] Microbial modulation of RIPK1-mediated regulated necrosis
[Pathway:R-HSA-5357905] Regulation of TNFR1 signaling
[Pathway:R-HSA-5626978] TNFR1-mediated ceramide production
[Pathway:R-HSA-5602636] IKBKB deficiency causes SCID
[Pathway:R-HSA-5357786] TNFR1-induced proapoptotic signaling
[Pathway:R-HSA-2562578] TRIF-mediated programmed cell death
[Pathway:R-HSA-9758274] Regulation of NF-kappa B signaling
[Pathway:R-HSA-5603027] IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
[Pathway:R-HSA-111464] SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
[Pathway:R-HSA-5357956] TNFR1-induced NF-kappa-B signaling pathway
[Pathway:R-HSA-5684264] MAP3K8 (TPL2)-dependent MAPK1/3 activation

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