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Mondo:0005812 Show undefined attributes

databaseName Mondo

dbId 11944910

displayName Mondo:0005812

identifier 0005812

referenceDatabase [ReferenceDatabase:11944889] Mondo

schemaClass DatabaseIdentifier

url https://monarchinitiative.org/MONDO:0005812

Referrals

(crossReference)

[Pathway:R-HSA-168333] NEP/NS2 Interacts with the Cellular Export Machinery
[GenomeEncodedEntity:R-FLU-9009966] FLUAV UpN-ssRNA [cytosol]
[EntityWithAccessionedSequence:R-FLU-188832] NP [nucleoplasm]
[Complex:R-HSA-9677228] NP:PARP1 [nucleoplasm]
[GenomeEncodedEntity:R-FLU-9684905] Influenza GU-rich ssRNA [endosome lumen]
[Complex:R-FLU-193302] vRNA (Genomic):NP Complex [nucleoplasm]
[OtherEntity:R-ALL-193039] Mature intronless transcript derived mRNA with m7G cap removed [nucleoplasm]
[DefinedSet:R-NUL-9684904] TLR7, TLR8 ligands [endosome lumen]
[ChemicalDrug:R-ALL-9733001] baicalein [cytosol]
[Complex:R-FLU-169245] Influenza A Viral Envelope [extracellular region]
[DefinedSet:R-NUL-9684903] GU-rich ssRNA [endosome lumen]
[DefinedSet:R-FLU-192988] viral mRNA [nucleoplasm]
[Complex:R-FLU-169143] NS1 dimer [cytosol]
[Complex:R-HSA-9686346] NS1:MLKL [cytosol]
[Complex:R-FLU-192682] cRNP [nucleoplasm]
[GenomeEncodedEntity:R-FLU-9028895] Influenza A dsRNA intermediate form [endosome lumen]
[Complex:R-FLU-192720] Viral Polymerase [nucleoplasm]
[Complex:R-FLU-169075] NS1:viral dsRNA Complex [cytosol]
[Complex:R-HSA-1176067] NS1 homodimer:Importin [nucleoplasm]
[OtherEntity:R-ALL-169703] Host Derived Lipid Bilayer Membrane Rich In Sphingolipids And Cholesterol [plasma membrane]
[GenomeEncodedEntity:R-FLU-6790580] Influenza A dsRNA intermediate form [cytosol]
[Complex:R-FLU-192756] Initiated vRNA Transcription Complex [nucleoplasm]
[OtherEntity:R-ALL-192638] Influenza cRNA (complete) [nucleoplasm]
[ChemicalDrug:R-ALL-9769516] amantadine [endocytic vesicle lumen]
[Pathway:R-HSA-168336] Uncoating of the Influenza Virion
[Pathway:R-HSA-169131] Inhibition of PKR
[Reaction:R-HSA-168878] PB1-F2 binds to the mitochondrial adenine nucleotide translocator 3 ANT3, inducing apoptosis
[Reaction:R-HSA-168857] Binding of vRNP:M1:NEP complex to CRM1 export receptor
[Pathway:R-HSA-168271] Transport of Ribonucleoproteins into the Host Nucleus
[Reaction:R-HSA-168875] Trimerization of HA
[Reaction:R-HSA-192912] NP binds vRNA
[Pathway:R-HSA-192869] cRNA Synthesis
[Reaction:R-HSA-168893] Binding of NEP/NS2 to vRNP:M1
[Reaction:R-HSA-168860] Membrane fusion
[BlackBoxEvent:R-HSA-168884] Hemagglutinin (HA) protein synthesis
[Reaction:R-HSA-168870] Neuraminidase enzymatic release from sialic acid
[Reaction:R-HSA-168871] Fusion of vesicle containing the HA trimer, NA tetramer and M2 tetramer to the Golgi apparatus
[Reaction:R-HSA-168313] Virion-associated M2 protein mediated ion infusion
[Reaction:R-HSA-168896] NS1 binds PKR
[Reaction:R-HSA-192925] Export of Spliced Viral mRNA
[Reaction:R-HSA-168324] Conformation change in hemagglutinin freeing the fusion peptide of HA2
[Reaction:R-HSA-168317] Recruitment of Karyopherin Beta to form a Trimeric Complex
[Reaction:R-HSA-192624] cRNA Extension
[Reaction:R-HSA-195726] Association of NA into rafts
[Reaction:R-HSA-168337] Docking and transport of the RNP:Karyopherin complex through the nuclear pore
[Reaction:R-HSA-168869] Budding of vesicle with the HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum into the cytosol
[BlackBoxEvent:R-HSA-1176059] Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus
[Reaction:R-HSA-5685600] viral HA binds NCRI
[Reaction:R-HSA-169847] Assembly of NA tetramers
[Pathway:R-HSA-168268] Virus Assembly and Release
[Reaction:R-HSA-168865] NA activation of TGF-beta
[Reaction:R-HSA-168326] Assembly of an Active Transcription Complex
[Reaction:R-HSA-168285] Clathrin-Mediated Pit Formation And Endocytosis Of The Influenza Virion
[Reaction:R-HSA-192627] Viral mRNA Export
[Pathway:R-HSA-168325] Viral Messenger RNA Synthesis
[Reaction:R-HSA-168306] Concerted hemagglutinin pore formation
[Reaction:R-HSA-168312] Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane
[Reaction:R-HSA-192746] Binding of M1 to vRNP
[Pathway:R-HSA-168330] Viral RNP Complexes in the Host Cell Nucleus
[Pathway:R-HSA-168277] Influenza Virus Induced Apoptosis
[Reaction:R-HSA-168894] Accumulation of M1 at the inner leaflet of the lipid bilayer
[Reaction:R-HSA-192781] Viral mRNA Splicing (M, NS segments)
[Reaction:R-HSA-168862] Association of HA into rafts
[Pathway:R-HSA-168303] Packaging of Eight RNA Segments
[Pathway:R-HSA-168316] Assembly of Viral Components at the Budding Site
[Pathway:R-HSA-168302] Budding
[Pathway:R-HSA-168888] Inhibition of IFN-beta
[Reaction:R-HSA-6791035] Release of NS1 homodimer
[BlackBoxEvent:R-HSA-168301] Elongation, Polyadenylation and Termination
[Reaction:R-HSA-188544] Assembly of M2 tetramers
[Reaction:R-HSA-192916] Initiation of vRNA Synthesis
[Reaction:R-HSA-169921] Glycosylation and Folding of HA
[Pathway:R-HSA-192814] vRNA Synthesis
[Reaction:R-HSA-192851] vRNA Extension
[Reaction:R-HSA-195739] Palmitoylation of cysteine residues on M2 in the cis-golgi network
[BlackBoxEvent:R-HSA-192704] Synthesis of PB1-F2
[BlackBoxEvent:R-HSA-195734] Neuraminidase (NA) synthesis
[Pathway:R-HSA-168288] Fusion of the Influenza Virion to the Host Cell Endosome
[Reaction:R-HSA-168880] vRNP Export through the nuclear pore
[Reaction:R-HSA-192830] Viral Polymerase Assembly
[Reaction:R-HSA-195730] Transport of processed viral proteins to the cell membrane
[Reaction:R-HSA-168895] RNP association
[Pathway:R-HSA-168275] Entry of Influenza Virion into Host Cell via Endocytosis
[Reaction:R-HSA-168280] Priming and Initiation of Transcription
[BlackBoxEvent:R-HSA-195733] M2 protein synthesis
[Pathway:R-HSA-168273] Influenza Viral RNA Transcription and Replication
[Pathway:R-HSA-168298] Release
[Reaction:R-HSA-168891] Binding of NS1 to dsRNA
[Reaction:R-HSA-168272] Binding of the influenza virion to the host cell
[Reaction:R-HSA-169919] Glycosylation of NA
[Pathway:R-HSA-168276] NS1 Mediated Effects on Host Pathways
[BlackBoxEvent:R-HSA-192841] Viral Protein Synthesis
[Pathway:R-HSA-192905] vRNP Assembly
[Reaction:R-HSA-168859] Binding of NS1 to cleavage and host polyadenylation specificity factor (CPSF)
[Pathway:R-HSA-168255] Influenza Infection
[Reaction:R-HSA-168310] Release of the RNP into the host cell nucleus
[Reaction:R-HSA-168297] Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein
[Pathway:R-HSA-168270] Fusion and Uncoating of the Influenza Virion
[Reaction:R-HSA-195926] Association with M1 at cell membrane
[Reaction:R-HSA-168299] Ribonucleoprotein release from M1 proteins
[Pathway:R-HSA-192823] Viral mRNA Translation
[Pathway:R-HSA-168874] Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus
[Reaction:R-HSA-192677] Newly synthesized vRNP for export
[Reaction:R-HSA-168882] Association of NP into rafts
[Reaction:R-HSA-168883] Binding of NS1 to poly(A)-binding protein II (PABII)
[Reaction:R-HSA-192832] Initiation of cRNA Synthesis
[Reaction:R-HSA-168858] Palmitoylation of cysteine residues on HA in the cis-Golgi network
[Pathway:R-HSA-168274] Export of Viral Ribonucleoproteins from Nucleus
[Pathway:R-HSA-168315] Inhibition of Host mRNA Processing and RNA Silencing
[Reaction:R-HSA-9686343] IAV NS1 binds MLKL
[Pathway:R-HSA-168305] Inhibition of Interferon Synthesis

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