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Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane Show undefined attributes

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category transition

compartment

created [InstanceEdit:168327] 2007年04月16日 22:35:07

crossReference

[DatabaseIdentifier:11944910] Mondo:0005812

dbId 168312

disease

[Disease:1660558] influenza

displayName Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane

eventOf

[Pathway:R-HSA-168288] Fusion of the Influenza Virion to the Host Cell Endosome - Homo sapiens

followingEvent

[Reaction:R-HSA-168306] Concerted hemagglutinin pore formation - Homo sapiens

goBiologicalProcess [GO_BiologicalProcess:6589] fusion of virus membrane with host plasma membrane

input

[Complex:R-FLU-189182] Influenza A Viral Particle With A Fusion Competent HA2 [endosome lumen]

isInDisease true

isInferred false

literatureReference

[LiteratureReference:189373] Membrane fusion mechanisms: the influenza hemagglutinin paradigm and its implications for intracellular fusion

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane

output

[Complex:R-FLU-189138] Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane [endocytic vesicle membrane]

precedingEvent

[Reaction:R-HSA-168324] Conformation change in hemagglutinin freeing the fusion peptide of HA2 - Homo sapiens

relatedSpecies

[Species:9031716] Influenza A virus

releaseDate 2006年01月23日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-168312

summation

[Summation:179374] The fusion peptide of its HA2 subunit interacts with the end...

updateTrackers

[UpdateTracker:9792483] Update Tracker - [Reaction:168312] Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane - v20:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9792483] Update Tracker - [Reaction:168312] Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane - v20:[addLiteratureReference, modifyText]

(hasEvent)

[Pathway:R-HSA-168288] Fusion of the Influenza Virion to the Host Cell Endosome

(precedingEvent)

[Reaction:R-HSA-168306] Concerted hemagglutinin pore formation

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