InnateDB: Systems Biology of the Innate Immune Response

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Homo sapiens Protein: ACE
Summary
InnateDB Protein	IDBP-382886.4
Last Modified	2014年10月13日 [Report errors or provide feedback]
Gene Symbol	ACE
Protein Name	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms	ACE1; CD143; DCP; DCP1; ICH; MVCD3;
Species	Homo sapiens
Ensembl Protein	ENSP00000387760
InnateDB Gene	IDBG-63266 (ACE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions	This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database. Experimentally validated Total 20 [view] Protein-Protein 19 Protein-DNA 1 Protein-RNA 0 DNA-DNA 0 RNA-RNA 0 DNA-RNA 0

Gene Ontology
Molecular Function

Accession GO Term

GO:0008237 metallopeptidase activity

GO:0008241 peptidyl-dipeptidase activity

Biological Process

GO:0006508 proteolysis

Cellular Component

GO:0016020 membrane

Protein Structure and Domains PDB ID InterPro IPR001548 Peptidase M2, peptidyl-dipeptidase A
PFAM PF01401
PRINTS PR00791
PIRSF SMART TIGRFAMs Post-translational Modifications Modification Cross-References SwissProt PhosphoSite PhosphoSite- TrEMBL Q3KRI5 UniProt Splice Variant Entrez Gene UniGene Hs.712079 RefSeq HUGO OMIM CCDS HPRD 00108 IMGT EMBL AC113554 AY999972 AY999973 GenPept ABA39228 ABA39229

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca