Reactome Pathway Database

Schema > Reaction > Entries

ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA Show undefined attributes

catalystActivity

[CatalystActivity:10435512] CoA-ligase activity of ACSM2B-like proteins [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10531387

displayName ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA

eventOf

[Pathway:R-SSC-9749641] Aspirin ADME - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-9750001] GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid - Sus scrofa

inferredFrom

[Reaction:R-HSA-9749971] ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA
2,5-DHBA + Coenzyme A + ATP => 2,5-DHBA-CoA + AMP + pyrophosphate
2,5-DHBA and Coenzyme A react to form 2,5-DHBA-CoA thioester

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-9749971

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-9749641] Aspirin ADME

(precedingEvent)

[Reaction:R-SSC-9750001] GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid

(inferredTo)

[Reaction:R-HSA-9749971] ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA

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