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ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA Show undefined attributes

authored

[InstanceEdit:9750966] Stephan, Ralf, 2021年08月17日

catalystActivity

[CatalystActivity:159441] CoA-ligase activity of ACSM2B-like proteins [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:9749991] Stephan, Ralf, 2021年08月09日

dbId 9749971

displayName ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA

edited

[InstanceEdit:9758462] Stephan, Ralf, 2021年11月12日

eventOf

[Pathway:R-HSA-9749641] Aspirin ADME - Homo sapiens

followingEvent

[Reaction:R-HSA-9750001] GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA
2,5-DHBA + Coenzyme A + ATP => 2,5-DHBA-CoA + AMP + pyrophosphate
2,5-DHBA and Coenzyme A react to form 2,5-DHBA-CoA thioester

negativePrecedingEvent

[NegativePrecedingEvent:9761240] Abundant Molecules: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid

orthologousEvent

output

precedingEvent

[BlackBoxEvent:R-HSA-9757456] 2,5-DHBA translocates from ER lumen to mitochondrial matrix - Homo sapiens

releaseDate 2021年12月08日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9756301] Huddart, Rachel, 2021年10月13日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9749971

summation

[Summation:9750703] ACSM2B-like enzymes catalyze the transfer of acyl groups ont...

Referrals

(hasEvent)

[Pathway:R-HSA-9749641] Aspirin ADME

(precedingEvent)

[Reaction:R-HSA-9750001] GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid

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