Fenamic acid
From Wikipedia, the free encyclopedia
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| Preferred IUPAC name
2-Anilinobenzoic acid | |
| Other names
N-phenylanthranilic acid
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| ECHA InfoCard | 100.001.879 Edit this at Wikidata |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C13H11NO2 | |
| Molar mass | 213.23 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Fenamic acid is an organic compound, which, especially in its ester form, is called fenamate.[1] : 458 serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid.[2] : 235 [3] : 17 [2]
Fenamic acid can be synthesized from 2-chlorobenzoic acid and can be converted into acridone.[4]
References
[edit ]- ^ Gupta, PK. Drug NomenclatureUnited States Adopted Names. Ch 27 in Remington: The Science and Practice of Pharmacy, Vol 1. Eds. David B. Troy, Paul Beringer. Lippincott Williams & Wilkins, 2006 ISBN 9780781746731
- ^ a b Sriram D, Yogeeswari P. Medicinal Chemistry, 2nd Edition. Pearson Education India, 2010. ISBN 9788131731444
- ^ Auburn University course material. Jack DeRuiter, Principles of Drug Action 2, Fall 2002 1: Non-Steroidal Antiinflammatory Drugs (NSAIDS)
- ^ C. F. H. Allen, G. H. W. McKee (1939). "Acridone". Organic Syntheses. 2: 6. doi:10.15227/orgsyn.019.0006.
