Integrating MAGMA gene-level genetic association scores with single-cell transcriptional perturbation profiles to identify cell-type- and state-specific genetic–transcriptomic convergence.
-
Updated
Aug 19, 2026 - Python
Integrating MAGMA gene-level genetic association scores with single-cell transcriptional perturbation profiles to identify cell-type- and state-specific genetic–transcriptomic convergence.
Reproducible pipeline for cross-GWAS identification of recurrent moderate-effect BRCA1/2 breast cancer modifier loci
This repository contains an end-to-end tumour-only somatic variant-calling pipeline (GATK Mutect2 + snpEff) for triple-negative breast cancer whole-exome data, focused on BRCA1/BRCA2/TP53, built on Google Colab via Visual Studio Code.
Lab profile
This repository contains an end-to-end, fully GUI/web-based dual-receptor molecular docking and ADMET profiling pipeline of four cyanobacterial natural products — scytonemin, phycocyanobilin, lyngbyabellin A and nostocarboline — against the BRCA2 DNA-binding domain using PyMOL, AutoDock Vina, PLIP, SwissADME, and ADMETlab 3.0.
To associate your repository with the brca2 topic, visit your repo's landing page and select "manage topics."