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Hydrocortamate

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Hydrocortamate
Clinical data
Trade names Magnacort, Ulcort
Other names11β,17α-Dihydroxy-3,20-dioxopregn-4-en-21-yl N,N-diethylglycinate
Routes of
administration
Topical
Pharmacokinetic data
Excretion Hepatic
Identifiers
  • [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,

    16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl]

    2-(diethylamino)acetate
CAS Number
PubChem CID
PubChem SID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.000.877 Edit this at Wikidata
Chemical and physical data
Formula C27H41NO6
Molar mass 475.626 g·mol−1
3D model (JSmol)
  • [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)COC(=O)CN(CC)CC
  • InChI=1S/C27H41NO6/c1-5-28(6-2)15-23(32)34-16-22(31)27(33)12-10-20-19-8-

    7-17-13-18(29)9-11-25(17,3)24(19)21(30)14-26(20,27)4/h13,19-21,24,30,

    33H,5-12,14-16H2,1-4H3
  • Key:FWFVLWGEFDIZMJ-UHFFFAOYSA-N

Hydrocortamate (brand names Magnacort, Ulcortis) is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties.[1] [2] It is used topically to treat inflammation due to corticosteroid-responsive dermatoses.[3]

References

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Glucocorticoids
Natural
Synthetic
Antiglucocorticoids
Synthesis modifiers
GR Tooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMs Tooltip Selective glucocorticoid receptor agonists)
Antagonists
Others

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