Jump to content
Wikipedia The Free Encyclopedia

Dipeptidase 2

From Wikipedia, the free encyclopedia
(Redirected from DPEP2)
Mammalian protein found in Homo sapiens
DPEP2
Identifiers
Aliases DPEP2 , MBD2, dipeptidase 2
External IDsOMIM: 609925; MGI: 2442042; HomoloGene: 49703; GeneCards: DPEP2; OMA:DPEP2 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr. Chromosome 16 (human) [1]
Band 16q22.1Start67,987,394 bp [1]
End68,000,586 bp [1]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • granulocyte

  • monocyte

  • blood

  • spleen

  • right lung

  • lymph node

  • bone marrow

  • upper lobe of left lung

  • testicle

  • appendix
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

64174

319446

Ensembl

ENSG00000167261

ENSMUSG00000053687

UniProt

Q9H4A9

Q8C255

RefSeq (mRNA)

NM_022355
NM_001324159
NM_001369657

NM_001301204
NM_001301205
NM_176913

RefSeq (protein)

NP_001311088
NP_071750
NP_001356586

NP_001288133
NP_001288134
NP_795887

Location (UCSC)Chr 16: 67.99 – 68 Mb n/a
PubMed search[2] [3]
Wikidata

Dipeptidase 2 (DPEP2) is a protein which in humans is encoded by the DPEP2 gene.[4]

DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation.[5]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167261Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003). "Identification of two additional members of the membrane-bound dipeptidase family". The FASEB Journal. 17 (10): 1313–5. doi:10.1096/fj.02-0899fje . PMID 12738806. S2CID 15252871.
  5. ^ "Entrez Gene: Dipeptidase 2".

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

3.4.11-19: Exopeptidase
3.4.11
3.4.13
3.4.14
3.4.15
3.4.16
3.4.17
Other/ungrouped
3.4.21-25: Endopeptidase
3.4.99: Unknown
Receptor
(ligands)
BLT Tooltip Leukotriene B4 receptor
BLT1 Tooltip Leukotriene B4 receptor 1
BLT2 Tooltip Leukotriene B4 receptor 2
CysLT Tooltip Cysteinyl leukotriene receptor
CysLT1 Tooltip Cysteinyl leukotriene receptor 1
CysLT2 Tooltip Cysteinyl leukotriene receptor 2
CysLTE Tooltip Cysteinyl leukotriene receptor E
Enzyme
(inhibitors)
5-LOX Tooltip Arachidonate 5-lipoxygenase
12-LOX Tooltip Arachidonate 12-lipoxygenase
15-LOX Tooltip Arachidonate 15-lipoxygenase
LTA4H Tooltip Leukotriene A4 hydrolase
LTB4H Tooltip Leukotriene B4 ω-hydroxylase
LTC4S Tooltip Leukotriene C4 synthase
LTC4H Tooltip Leukotriene C4 hydrolase
LTD4 Tooltip Leukotriene D4 hydrolase
Others


Stub icon

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

AltStyle によって変換されたページ (->オリジナル) /