C. albicans OBPA/C5_01770C Summary

Last curated 2023年01月19日
See the Literature Guide for most recent publications.

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Summary
Locus History Literature Gene Ontology Phenotype Homologs Protein
OBPA BASIC INFORMATION [ View References ]
Standard Name OBPA1
Systematic Name, Reference Strain C5_01770C_A (C. albicans SC5314)
Assembly 19/21 Identifier orf19.3198
Alias OSH72
IPF9854.23 , IPF11167.13 , Contig4-1502_00014 , Contig4-1611_00014 , Contig4-2559_00104 , orf6.18815 , CA07593 , CaO19.31986 , OBPa6 , IPF111673 , orf19.3198, C5_01770C_B, C5_01770C
Feature Type ORF, Verified
Description Putative oxysterol binding protein; non-sex gene located within the MTLa mating-type-like locus; Plc1p-regulated (1, 7, 8)
Literature
CUG Codons 0
Systematic Names Used in Other Strains CAWG_04562 (C. albicans WO-1)
Orthologous genes in Candida species C. auris B8441 Ortholog(s) : B9J08_001454
C. parapsilosis CDC317 Ortholog(s) : CPAR2_303570
C. dubliniensis CD36 Ortholog(s) : Cd36_51550/OPBalpha
C. glabrata CBS138 Ortholog(s) : CAGL0K02849g
View ortholog cluster : 19 genes among 19 Candida-related species/strains
Ortholog(s) in non-CGD species S. pombe (SPCC23B6.01c) ; S. cerevisiae (OSH7)
Best hit(s) in non-CGD species A. nidulans (AN3807) ; N. crassa (NCU03258)
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JBrowse for feature C5_01770C_A

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GO Annotations View all OBPA GO evidence and references

Molecular Function
Manually curated * molecular_function unknown (ND)

Biological Process
Manually curated * biological process involved in interspecies interaction between organisms (IMP)
* single-species biofilm formation on inanimate substrate (IMP)

Cellular Component
Manually curated * cellular_component unknown (ND)
Mutant Phenotype View all OBPA Phenotype details and references
Classical genetics
heterozygous null * biofilm formation: decreased
* virulence: decreased

homozygous null * invasive growth: normal

Large-scale survey
heterozygous null * viable

null * viable

Sequence Information Ca22chr5A_C_albicans_SC5314:400071 to 398770 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2014年06月24日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to1302400,071to398,7702014年06月24日2014年06月24日

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Maps & Displays
Sequence Information Ca22chr5A_C_albicans_SC5314:400071 to 398770 | JBrowse
Note: this feature is encoded on the Crick strand.
External Links CGOB | Entrez Gene | Fungal Orthologs | FungiDB | GenBank (1, 2, 3) | Non-periodic Expression | Pedant | PhylomeDB | SwissProt | TrEMBL
Primary CGDID CAL0000179350
ADDITIONAL INFORMATION for OBPA
Gene/Sequence Resources
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for OBPA]
1) Hull CM and Johnson AD (1999) Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science 285(5431):1271-5
CGD Papers Entry Pubmed Entry Reference LINKOUT
2) Basante-Bedoya MA, et al. (2022) Two distinct lipid transporters together regulate invasive filamentous growth in the human fungal pathogen Candida albicans. PLoS Genet 18(12):e1010549
CGD Papers Entry Pubmed Entry
3) CandidaDB
CGD Papers Entry
4) Berman J (2005) Mapping of ORFs in Assembly 4 to those in Assembly 19.
CGD Papers Entry
5) CGD (2005) CGD comparison of orf6 and orf19 predicted protein products.
CGD Papers Entry
6) Maglott D, et al. (2007) Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res 35(Database issue):D26-31
CGD Papers Entry Pubmed Entry Reference LINKOUT Reference LINKOUT Reference LINKOUT Reference LINKOUT Reference LINKOUT
7) Kunze D, et al. (2005) Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans. Microbiology 151(Pt 10):3381-94
CGD Papers Entry Pubmed Entry Reference LINKOUT
8) Srikantha T, et al. (2012) Nonsex genes in the mating type locus of Candida albicans play roles in a/alpha biofilm formation, including impermeability and fluconazole resistance. PLoS Pathog 8(1):e1002476
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