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Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 Show undefined attributes

catalystActivity

[CatalystActivity:10612253] NADH dehydrogenase (ubiquinone) activity of Complex I [mitochondrial inner membrane]

category transition

compartment

[Compartment:70616] mitochondrial inner membrane

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10612259

displayName Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2

eventOf

[Pathway:R-XTR-611105] Respiratory electron transport - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

goBiologicalProcess [GO_BiologicalProcess:15809] mitochondrial electron transport, NADH to ubiquinone

inferredFrom

[Reaction:R-HSA-163217] Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2
NADH enters the respiratory chain at Complex I

output

precedingEvent

regulatedBy

[PositiveRegulation:10612260] Positive regulation by 'COQ10A,B [mitochondrial inner membrane]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-163217

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-611105] Respiratory electron transport

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-163217] Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2

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