Reactome Pathway Database

Schema > Reaction > Entries

PTPN6 dephosphorylates JAK3 Show undefined attributes

catalystActivity

[CatalystActivity:10467864] protein tyrosine phosphatase activity of PTPN6 [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10529876

displayName PTPN6 dephosphorylates JAK3

eventOf

[Pathway:R-SSC-201556] Signaling by ALK - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9701507] PTPN6 dephosphorylates JAK3 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PTPN6 dephosphorylates JAK3

output

precedingEvent

[Reaction:R-SSC-9701488] Active ALK phosphorylates JAK3 - Sus scrofa

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-9701507

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-201556] Signaling by ALK

(inferredTo)

[Reaction:R-HSA-9701507] PTPN6 dephosphorylates JAK3

© 2025 Reactome

Cite Us!