Reactome Pathway Database

Schema > Reaction > Entries

Activated FGFR4:p-FRS bind to PPTN11 Show undefined attributes

category binding

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10498245

displayName Activated FGFR4:p-FRS bind to PPTN11

eventOf

[Pathway:R-SSC-5654712] FRS-mediated FGFR4 signaling - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-8941613] Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange - Sus scrofa
[Reaction:R-SSC-5654655] Activated FGFR4 phosphorylates PPTN11 - Sus scrofa

inferredFrom

[Reaction:R-HSA-5654658] Activated FGFR4:p-FRS bind to PPTN11 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Activated FGFR4:p-FRS bind to PPTN11

output

[Complex:R-SSC-5654337] Activated FGFR4:p-FRS:PTPN11 [plasma membrane]

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-5654658

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-5654712] FRS-mediated FGFR4 signaling

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-5654658] Activated FGFR4:p-FRS bind to PPTN11

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