Reactome Pathway Database

Schema > Reaction > Entries

1-acyl LPA is acylated to PA by AGPAT (LPAAT) Show undefined attributes

catalystActivity

[CatalystActivity:11037141] 1-acylglycerol-3-phosphate O-acyltransferase activity of AGPAT [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

dbId 11037143

displayName 1-acyl LPA is acylated to PA by AGPAT (LPAAT)

eventOf

[Pathway:R-SCE-1483166] Synthesis of PA - Saccharomyces cerevisiae

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

1-acyl LPA is acylated to PA by AGPAT (LPAAT)
1-acyl-glycerol 3-phosphate + acyl-CoA => 1,2-diacyl-glycerol 3-phosphate + CoASH
lysophosphatidic acid + fatty acyl CoA => phosphatidic acid + CoA (1)

output

precedingEvent

[Reaction:R-SCE-1482656] PA is hydrolysed to 1-acyl LPA by PLA2[1] - Saccharomyces cerevisiae

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68322] Saccharomyces cerevisiae

stId R-SCE-75885

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SCE-1483166] Synthesis of PA

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT)

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