Reactome Pathway Database

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Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Show undefined attributes

compartment

[Compartment:984] extracellular region

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10198441

displayName Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

eventOf

[TopLevelPathway:R-RNO-392499] Metabolism of proteins - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

hasDiagram true

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-381426] Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Regulation of IGF Activity by IGFBP

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48895] Rattus norvegicus

stId R-RNO-381426

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[TopLevelPathway:R-RNO-392499] Metabolism of proteins

(hasEncapsulatedEvent)

(inferredTo)

[Pathway:R-HSA-381426] Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

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