Reactome Pathway Database

Schema > Reaction > Entries

Hydrolysis of choloyl-CoA to cholate and CoASH Show undefined attributes

catalystActivity

[CatalystActivity:10102279] acyl-CoA hydrolase activity of ACOT8 [peroxisomal matrix]

category transition

compartment

[Compartment:17951] peroxisomal matrix

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10102281

displayName Hydrolysis of choloyl-CoA to cholate and CoASH

eventOf

[Pathway:R-RNO-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Hydrolysis of choloyl-CoA to cholate and CoASH

output

precedingEvent

[Reaction:R-RNO-192341] Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA - Rattus norvegicus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-193385

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

(inferredTo)

[Reaction:R-HSA-193385] Hydrolysis of choloyl-CoA to cholate and CoASH

© 2025 Reactome

Cite Us!