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Entries
Hydrolysis of choloyl-CoA to cholate and CoASH
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authored
[InstanceEdit:193475] D'Eustachio, P, 2007年02月17日 19:40:28
catalystActivity
[CatalystActivity:193529] acyl-CoA hydrolase activity of ACOT8 [peroxisomal matrix]
category
transition
compartment
[Compartment:17951] peroxisomal matrix
created
[InstanceEdit:193476] D'Eustachio, P, 2007年02月19日 17:36:33
crossReference
[DatabaseIdentifier:12611278] Rhea:14542
dbId
193385
displayName
Hydrolysis of choloyl-CoA to cholate and CoASH
edited
[InstanceEdit:193475] D'Eustachio, P, 2007年02月17日 19:40:28
eventOf
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Homo sapiens
followingEvent
[BlackBoxEvent:R-HSA-193399] Cholate is translocated from the peroxisomal matrix to the cytosol - Homo sapiens
input
[SimpleEntity:R-ALL-192356] choloyl-CoA [peroxisomal matrix]
[SimpleEntity:R-ALL-141343] H2O [peroxisomal matrix]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:193464] Characterization of an acyl-coA thioesterase that functions as a major regulator of peroxisomal lipid metabolism
[LiteratureReference:193495] Identification of peroxisomal acyl-CoA thioesterases in yeast and humans
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
Hydrolysis of choloyl-CoA to cholate and CoASH
orthologousEvent
[Reaction:R-SCE-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Saccharomyces cerevisiae
[Reaction:R-CEL-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Caenorhabditis elegans
[Reaction:R-GGA-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Gallus gallus
[Reaction:R-XTR-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Xenopus tropicalis
[Reaction:R-DRE-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Danio rerio
[Reaction:R-SSC-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Sus scrofa
[Reaction:R-BTA-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Bos taurus
[Reaction:R-CFA-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Canis familiaris
[Reaction:R-RNO-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Rattus norvegicus
[Reaction:R-MMU-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Mus musculus
output
[SimpleEntity:R-ALL-193451] CCA [peroxisomal matrix]
[SimpleEntity:R-ALL-193514] CoA-SH [peroxisomal matrix]
precedingEvent
[Reaction:R-HSA-192341] Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA - Homo sapiens
releaseDate
2007年05月15日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:197117] D'Eustachio, P, 2007年04月30日 14:43:26
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-193385
summation
[Summation:193515] The peroxisomal matrix enzyme acyl-coenzyme A thioesterase 8...
updateTrackers
[UpdateTracker:9776692] Update Tracker - [Reaction:193385] Hydrolysis of choloyl-CoA to cholate and CoASH - v74:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9776692] Update Tracker - [Reaction:193385] Hydrolysis of choloyl-CoA to cholate and CoASH - v74:[modifyText]
(precedingEvent)
[BlackBoxEvent:R-HSA-193399] Cholate is translocated from the peroxisomal matrix to the cytosol
(hasEvent)
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
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