Reactome Pathway Database

Schema > Pathway > Entries

COX reactions Show undefined attributes

compartment

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10197461

displayName COX reactions

eventOf

[Pathway:R-RNO-211945] Phase I - Functionalization of compounds - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:9971] prostanoid metabolic process

hasDiagram false

hasEHLD false

hasEvent

[Reaction:R-RNO-140355] Arachidonate is oxidised to PGG2 by PTGS1 - Rattus norvegicus
[Reaction:R-RNO-140359] PGG2 is reduced to PGH2 by PTGS1 - Rattus norvegicus

inferredFrom

[Pathway:R-HSA-140180] COX reactions - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

COX reactions

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48895] Rattus norvegicus

stId R-RNO-140180

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-211945] Phase I - Functionalization of compounds

(inferredTo)

[Pathway:R-HSA-140180] COX reactions

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