Reactome Pathway Database

Schema > BlackBoxEvent > Entries

Active ALK recruits PI3K Show undefined attributes

category omitted

compartment

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9984697

displayName Active ALK recruits PI3K

eventOf

[Pathway:R-MMU-201556] Signaling by ALK - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-201510] PI3K synthesizes PIP3 downstream of ALK - Mus musculus

inferredFrom

[BlackBoxEvent:R-HSA-201515] Active ALK recruits PI3K - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Active ALK recruits PI3K

output

[Complex:R-MMU-9699995] Active ALK:PI3K [plasma membrane]

precedingEvent

[Reaction:R-MMU-201521] ALK autophosphorylation - Mus musculus

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:48892] Mus musculus

stId R-MMU-201515

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-201556] Signaling by ALK

(precedingEvent)

[Reaction:R-MMU-201510] PI3K synthesizes PIP3 downstream of ALK

(inferredTo)

[BlackBoxEvent:R-HSA-201515] Active ALK recruits PI3K

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