Reactome Pathway Database

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Activation of ATR in response to replication stress Show undefined attributes

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10080628

displayName Activation of ATR in response to replication stress

eventOf

[Pathway:R-MMU-69481] G2/M Checkpoints - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:7962] DNA replication

hasDiagram false

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-176187] Activation of ATR in response to replication stress - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Activation of ATR in response to replication stress

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48892] Mus musculus

stId R-MMU-176187

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-69481] G2/M Checkpoints

(inferredTo)

[Pathway:R-HSA-176187] Activation of ATR in response to replication stress

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